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TCP Retransmits over industrial network

Hello everyone, Wireshark neophite here with a question.
We have four HP Windows 10 clients and two HP windows 2019 servers on an industrial network. Over the course of 2 or 3 days the clients become lethargic in response to mouse/keyboard clicks and require rebooting. I have run wireshark on one of the clients to check the network traffic and I see what looks to me like quite a few TCP retransmissions (1 or 2 per second). The capture can be found here: https://www.dropbox.com/scl/fi/1cxmc2umjceke6qoepgls/unit33_server1.pcapng?rlkey=fuab76l2zyklig39v79z6am2b&dl=0
The physical layer looks like this: client - fiber converter - patch panel - Cisco SF350 - server.
In the capture the client ip is .33 and the server is .131
Is this retransmit frequency normal?
Does this capture provide any clues where I should look next, physical layer, NIC settings, Cisco, etc?
Any help would be greatly appreciated!