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There is packet-loss in your trace. Sometimes even a period of a few seconds in which there is no communication between this client and server. As I see you are using DSCP markings and you said that the problem only effects Citrix, could you check whether you might oversubscribe the queue reserved for Citrix (marked DSCP = 18, AF21)? Also please check with your MPLS provider whether their queue(s) for AF21 marked traffic might have drops.
